immp1l inner mitochondrial membrane peptidase subunit 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: immp1lprovided by ZNC
Official Full Name: inner mitochondrial membrane peptidase subunit 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-070522-4
See related: Ensembl:ENSDARG00000045935 AllianceGenome:ZFIN:ZDB-GENE-070522-4
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable serine-type endopeptidase activity and serine-type exopeptidase activity. Predicted to be involved in protein processing involved in protein targeting to mitochondrion. Predicted to act upstream of or within proteolysis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of mitochondrial inner membrane peptidase complex. Orthologous to human IMMP1L (inner mitochondrial membrane peptidase subunit 1). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 7

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	GRCz11 (GCF_000002035.6)	7	NC_007118.7 (16033927..16064685)
105	previous assembly	GRCz10 (GCF_000002035.5)	7	NC_007118.6 (15781954..15812945)

Chromosome 7 - NC_007118.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables peptidase activity	IEA Inferred from Electronic Annotation more info
enables serine-type endopeptidase activity	IEA Inferred from Electronic Annotation more info
enables serine-type peptidase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in protein processing involved in protein targeting to mitochondrion	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within proteolysis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within signal peptide processing	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
part_of mitochondrial inner membrane peptidase complex	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mitochondrial inner membrane protease subunit 1

Names: IMP1 inner mitochondrial membrane peptidase-like

XP_001335263.1

EC 3.4.21.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001386390.1 → NP_001373319.1 mitochondrial inner membrane protease subunit 1 isoform 1

Status: VALIDATED

Source sequence(s)

CT030217

Conserved Domains (1) summary

cd06530
Location:32 → 141

S26_SPase_I; The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are ...
NM_001386391.1 → NP_001373320.1 mitochondrial inner membrane protease subunit 1 isoform 2

Status: VALIDATED

Source sequence(s)

CT030217

Conserved Domains (1) summary

cd06530
Location:32 → 122

S26_SPase_I; The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are ...

RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007118.7 Reference GRCz11 Primary Assembly

Range

16033927..16064685

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_001335227.7 → XP_001335263.1 mitochondrial inner membrane protease subunit 1

UniProtKB/TrEMBL

A0A8M1PYZ0, E7FGX8

Related

ENSDARP00000100201.2, ENSDART00000114062.4

Conserved Domains (2) summary

cd06530
Location:57 → 166

S26_SPase_I; The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are ...

TIGR02227
Location:54 → 172

sigpep_I_bact; signal peptidase I, bacterial type